Letter: Phenobarbitone in neonatal jaundice.

Phenobarbitone in neonatal jaundice.

Sinniah, D., Tay, L. K., and Dugdale, A. E. (1971). Archives of Disease in Childhood, 46, 712. Phenobarbitone in neonatal jaundice. Eighty-three jaundiced newborn infants were studied, 41 received phenobarbitone, and 42 served as controls. 48 hours after starting treatment the mean serum bilirubin level of the group of normal birthweight infants was significantly lower than that of controls. Ex...

Relative roles of phototherapy and phenobarbitone in treatment of nonhaemolytic neonatal jaundice.

Phenobarbitone in Neonatal Seizures: Controversies

Seizures are defined clinically as a paroxysmal alteration in neurologic function, i.e., motor, behaviour and/or autonomic function. Seizures are the most important signal of neurological disease in the neonatal period. They occur in 1-5% of the new-borns. The incidence is higher during this period than in any other period in life. It is important to treat seizures because of the potential adve...

Phenobarbitone dosage in neonatal convulsions.

In order to find the optimal dosage schedule of phenobarbitone for neonatal convulsions, four groups of patients were studied. Twelve infants (group 1) received a mean phenobarbitone dose of 9.5 mg/kg a day given intramuscularly for 3 days followed by 5.8 mg/kg a day given intramuscularly and then orally. Six infants (group 2) received a mean intravenous loading dose of 9.5 mg/kg followed by 6....

Neonatal jaundice.

This article discusses the production, transport, and excretion of bilirubin in the newborn period. The causes, significance, and treatment of unconjugated and conjugated hyperbilirubinemia are different; and because this is so, it is important to review the main causes and management of unconjugated hyperbilirubinemia. Conjugated hyperbilirubinemia in the newborn period could be either due to ...